��ɫ��Ƶ

By Terrence Wade

(April 26, 2016) — The ��ɫ��Ƶ Colleges of  and  are proud to have Nobel Prize Winner Frank Wilczek on campus this week as he delivers his lecture “Some Intersections of Art and Science.” The lecture will take place at 7:30 p.m. Thursday, April 28, at Memorial Hall. The event is free and open to the public.

The lecture will cover topics of profound reasons rooted in the nature of human cognition and perception and why art and science have a lot to offer one another. Wilczek will display some important historical examples of their synergy and point out some emerging opportunities. Several striking images will be an integral part of the

By Whitney Harder

(April 25, 2016) — A new instrument to be developed by ��ɫ��Ƶ researchers will overcome current limitations in fluorescence microscopy and could accelerate basic scientific discoveries. The multimodal and cost-effective imaging and data collection platform is being funded by a three-year, $589,250 National Science Foundation (NSF) grant from the Instrument Development for Biological Research (IDBR) program.

Total internal reflection fluorescence (TIRF) microscopy and fluorescence correlation spectroscopy (FCS) have become essential tools to understand biochemical and cellular processes. But these tools are limited — they are often highly labor intensive and thus have been primarily restricted to single sample analysis followed by costly manual data processing. 

By Whitney Hale

This year's selection of a dozen UK students and alumni for NSF Graduate Research Fellowships is believed to be the largest in the school's history and is four times the number of selections for 2015. To put more of emphasis on the fellowship

By Whitney Hale

(April 14, 2015) — A ��ɫ��Ƶ senior and recent graduate have been selected for fellowships from the  program. As part of the program,  senior Calvin Hong and 2015  and  graduate Brittney Woodrum will teach in Hong Kong and Myanmar respectively.

Princeton in Asia (PiA) sponsors more than 150 fellowships and internships in 20 countries and is the oldest and largest organization of its kind, unique in its scope, size, century-long

Ryan Loe has been selected to participate in the This award will allow Ryan to visit the University of Queensland for a research stay this summer with joint support from the National Science Foundation and the Australian Academy of Science.  Loe is a graduate student in the Crocker group at the ��ɫ��Ƶ.

Corrine Elliott was awarded a .  The Barry Goldwater Scholarship and Excellence in Education Program was established by Congress in 1986 to honor Senator Barry Goldwater, who served his country for 56 years as a soldier and statesman, including 30 years of service in the U.S. Senate. The purpose of the Foundation is to provide a continuing source of highly qualified scientists, mathematicians, and engineers by awarding scholarships to college students who intend to pursue research careers in these fields. This prestigious scholarship was awarded to only two students in the state of Kentucky.

Elliott is an undergraduate chemistry and mathematics major at the ��ɫ��Ƶ and conducts research under the guidance of Prof. Susan Odom and Prof.

John Hoben's abstract has been selected for a podium presentation at the Southeast Enzymes Conference in Atlanta, GA, in April. This regional meeting has established a reputation for excellence in the area of enzymology.  Hoben's presentation titled "  highlights research done in Prof. Anne-Frances Miller's research group in the Department of ��ɫ��Ƶ at the ��ɫ��Ƶ  in collaboration with students Karl Hempel and Zacchary Griffin.

Graduate student Erin Wachter was awarded an American Chemical Society Student Travel Award to present her research in two talks at the 251st ACS National Meeting in San Diego, CA. The award was provided by the Division of Inorganic ��ɫ��Ƶ.  The titles of Erin's presentations include "Using a Ru(II) building block and a rapid screening approach to identify nucleic acid selective “light switch” compounds" and "Structural features that influence photochemical reactivity and phototherapeutic activity of Ru(II) polypyridyl complexes".

Wachter is a graduate student in Prof. Edith Glazer's research group in the Department of ��ɫ��Ƶ at the ��ɫ��Ƶ.

Prof. Edith Glazer's publication titled "Light-Sensitive Ruthenium Complex-Loaded Cross-Linked Polymeric Nanoassemblies for the Treatment of Cancer" was selected as a Hot Article for 2015 in the Journal of Materials ��ɫ��Ƶ B, and as such it has been included in the Hot Article 2015 web collection, which can be viewed .  This publication reports the preparation and analysis of polymer nanoassemblies as potential carrier systems for cytotoxic ruthenium complexes.  Glazer and coworkers found that electrostatic and hydrophobic interactions with the complexes impact release rates and percentages, as well as biological activity.

full citation: Matthew Dickerson, Brock Howerton, Younsoo Bae and Edith C.

Prof. John Anthony's publication titled "The Effect of Regioisomerism on the Crystal Packing and Device Performance of Desymmetrized Anthradithiophenes" was selected as a Hot Article for 2015 in the Journal of Materials ��ɫ��Ƶ C, and as such it has been included in the Hot Article 2015 web collection, which can be viewed .  This publication showcases a new class of anthradithiophene derivatives, which are typically synthesized as an inseparable mixture of regioisomers.  The Anthony group reported a synthesis of desymmetrized anthradithiophenes that enabled the chromatographic separation of the resultant isomers and - in collaboration with Prof. Lynn Loo's group at Princeton University - found that certain pairs of

Corrine "Nina" Elliott, an undergraduate student majoring in chemistry and mathematics at UK, is the receipient of a Summer Undergraduate Research Fellowship (SURF) from the American Chemical Soceity's Division of Organic ��ɫ��Ƶ.  This $5,000 fellowship will allow Corrine to continue research in the ��ɫ��Ƶ Department at the ��ɫ��Ƶ for the Summer of 2016. Corrine's research proposal titled "Steric Manipulation of Small-Molecule Oxidation Potentials for Energy-Storage Applications" involves the design of synthesis of phenothiazine derivatives targeted at overcharge protection of high-voltage cathodes in lithium-ion batteries.  Her proposal is based on preliminary results under the guidance of faculty mentors Susan Odom and Chad Risko.  

Since the discovery of nickel-catalyzed cyclization of acetylene to benzene and cyclooctatetraene, transition-metal-activated cycloaddition of alkynes has become a powerful technique to construct ring compounds in organic synthesis. Although cyclo-trimerization and -tetramerization were discovered almost 70 years ago, direct metal-mediated acetylene oligomerization to polycyclic compounds has not been reported. Instead, cycloaddition of different alkynes, or alkynes with alkenes or arynes, has been used to synthesize polycyclic and other complex ring structures. In a recent Journal of American Chemical Society Communication, the Yang group reported the metal-activated bicycle-oligomerization of acetylene to naphthalene in a supersonic molecular beam experiment. In their work, laser-vaporized lanthanum atoms are used to activate acetylene molecules, naphthalene is detected in the form

Three chemistry undergraduate researchers from the ��ɫ��Ƶ, along with more than 200 other student representatives from across the state, presented their research Frankfort, KY, on February 25th to showcase their research to the state legislature at Posters at the Capitol.  

is a a one-day annual event held to educate the Kentucky state legislators of the importance of undergraduate research and scholarly work.  The governor, members of the General Assembly, and representatives from students' hometowns are able to engage directly with the scholars on this day. The following students from the Department of ��ɫ��Ƶ presented their research.

Amir Kucharski: “Understanding Ion Binding Anity and Selectivity in Beta Parvalbumin Using Molecular Dynamics and Mean Sphere

Erin Wachter was just awarded the The Myrle E. and Verle D. Nietzel Visiting Distinguished Faculty Program Award to support bringing Dr. Christine Cardin, Professor of Crystallography at the University of Reading, to UK to serve as the outside examiner for the thesis defense. This award enriches the dissertation experience for selected doctoral students whose dissertations are judged to be especially meritorious and also promotes to academic leaders at other institutions the high quality of scholarship achieved by our doctoral students. Moreover, the program serves to enhance the overall intellectual and research environment at the ��ɫ��Ƶ through colloquia offered by some of the world’s exemplary scholars.

Wachter is a graduate student in Prof. Edith Glazer's research group in the Department of

On February 22, 2016 John Anthony, a ��ɫ��Ƶ professor at the ��ɫ��Ƶ had an article featured in the Nature Communications publication.  The article titled, "Reducing dynamic disorder in small-molecule organic semiconductors by suppressing large-amplitude thermal motions," deals with understanding performance vibrations in organic semiconductors.

All solids are composed of atoms or molecules, and at temperatures above absolute 0 (-460 °F) these molecules are vibrating rapidly.  Such vibrations decrease the performance of semiconductors (critical components in computer chips and modern video displays), because the movement of the molecules can deflect charges moving through the solid.      

Anthony's work with researchers in England and Belgium, investigates the specific nature of these vibrations and their impact on charge being

The editors of the journal Energy Technology named an article by ��ɫ��Ƶ ��ɫ��Ƶ Professor Susan Odom one of the top 10 articles of 2015.  Odom’s publication, "A Highly Soluble Organic Catholyte for Non-Aqueous Redox Flow Batteries," was selected based on the number of downloads and citations, and the feedback of the journal’s editorial office Energy Technology publishes articles covering all technical aspects of energy process engineering from different angles. Due to the selection of Odom’s article, it is accessible for free of charge via the Wiley online library until the end of 2016: 

Dr. Susan Odom is an Assistant Professor in the Department of ��ɫ��Ƶ.  In addition to teaching

In a collaboration with the University of Minnesota, Stanford University, Georgia Institute of Technology, King Abdullah University of Science and Technology (KAUST), and Oak Ridge National Laboratory (ORNL), Assistant Professor of ��ɫ��Ƶ Chad Risko published an article titled “Strain Effects on the Work Function of an Organic Semiconductor” in Nature Communications. The combined experimental and theoretical effort sought to establish relationships between strain and the work functions of organic semiconductors, important connections for developing fundamental insights into the electrical properties of organic thin films. The results of this study will have broad impact for the development of next generation flexible electronic devices.

Link to article:  

Alexis Eugene was recognized for her research at the held in December 2015.  Her poster presentation titled "Photochemistry of alpha-keto acids in model atmospheric waters" received recognition as one of the two best graduate student posters.

Alexis is a graduate student in Prof. Marcelo Guzman's group in the Department of ��ɫ��Ƶ at UK whose work has been published in Atmospheric ��ɫ��Ƶ and Physics and Proceedings of the National Academy of Science of the United States of America.

The beginning of the new year marks a celebration of mentoring at the National Science Foundation through the recognition of mentors via PAESMEM: the Presidential Award for Excellence in Science, Mathematics, & Engineering Mentoring.  A recent article published by the National Science Foundation featured PAESMEM alumni, including ��ɫ��Ƶ Professor D. Allan Butterfield, on the subject of what makes a good mentor and why mentoring matters.  Says Butterfield: "Maximizing STEM educational and research opportunities for all citizens of this country - regardless of race, ethnicity, gender, sexual orientation, religious preference, or socioeconomic status - directly benefits the U.S. economic enterprise. To exclude or minimize opportunities for any diminishes all of us."

Click

By Charles Wright, Whitney Harder

(Jan. 11, 2015) — ��ɫ��Ƶ Department of ��ɫ��Ƶ researchers Edith Glazer, Sean Parkin and students Erin Wachter and Diego Moyá recently published a study showing that specialized compounds containing the metal ruthenium may be able to visualize or damage specific DNA structures relevant for cancer.

Published in "��ɫ��Ƶ - A European Journal," the work was named a "Hot Paper" for its importance in a rapidly evolving field of high interest, and was highlighted with the back cover.

The ends of chromosomes and some genes associated with cancer have regions where DNA can form